10021 - Clinically Relevant Pathology of the Placenta - Part II

Course Director

Jonathan Hecht, M.D., Ph.D., Harvard Medical School


Inadequate experience in diagnosing pathologic changes in the placenta can lead to confusing and imprecise reports, unnecessary maternal testing and concern, and even inappropriate intervention such as anticoagulation in the mother or antibiotic prophylaxis on the baby.

This two part course illustrates common histologic abnormalities of the placenta with clinical correlates. Suggestions for diagnostic terminology and specific clinical follow-up are provided.

This Part II builds upon the material in Part I and covers findings that add significant value to explain fetal complications and predict recurrence.


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

1.25 ABP CC/MOC Credits1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: $32.50

Course Dates

Last Review Date: 08-Jun-2023
Expiration Date: 07-Jun-2026


1. Present common microscopic abnormalities of the placenta, grouped by clinical indication for the examination.

2. Offer guidelines for diagnosis and reporting of common placental abnormalities.

3. Present, in parallel, mimics of clinically important diagnoses.


Explain fetal complications and predict recurrence:

1. Chorioamnionitis

2. Intrauterine growth restriction

   • Chronic abruption

   • Poor maternal perfusion, placental insufficiency

   • Fetal Thrombosis

3. Maternal thrombosis or hemorrhage and thrombophilia

4. Villitis of uncertain etiology

5. Cord accident

6. Preeclampsia

7. Infarction

8. Increased syncytial knots

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include chorioamnionitis, placental abscesses, funisitis, intrauterine growth restriction, fetal growth restriction, poor maternal perfusion, placental insufficiency, perivillous fibrin deposition, maternal floor infarction, placental hematoma, intervillous thrombus, fetal thrombosis, maternal thrombosis, or maternal hemorrhage, thrombophilia, villitis of uncertain etiology, cord accident, preeclampsia, placental infarction, syncytial knots, periventricular leukomalacia, fetal thrombotic vasculopathy, Tenney-Parker change, decidual vasculopathy, fetal vascular compromise, and marginal membranous cord insertion.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)
☑  Practice-Based Learning (PBL)

Financial Relationship Disclosure and Content Attestation

Dr. Jonathan L. Hecht attests that he has no financial relationships with a commercial entity producing health-care related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not produce health-care related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that produce health care-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 CC/MOC credits for the American Board of Pathology (ABP) Continuing Certification (CC) / Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn CC/MOC credits equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABP CC/MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.