10025 - Series: B-cell Lymphoma: An image intensive guide to work-up and classification


Understanding the key diagnostic steps for diagnosing lymphoid malignancies is essential for pathologists to arrive at accurate diagnosis of B- and T-cell malignancies. This complex evaluation requires integration of clinical, histologic, immunophenotypic, and molecular characteristics. Image-intensive sources that illustrate the key diagnostic criteria are not easily found in current textbooks. This series of courses is designed to guide Surgical Pathologists, Hematopathologists, and trainees through a method algorithm for diagnosis and classification of B-cell lymphomas.

Courses in the Series

(Click on course name below for information.)


For Surgical Pathologists, Hematopathologists, and trainees to:

1. Recognize malignant lymphoid proliferations.

2. Effectively and efficiently utilize immunohistochemistry and molecular testing to supplement light microscopic evaluation of lymphoid proliferations.

3. Properly classify B-cell lymphomas.


Part 1

1. Small lymphocytic lymphoma

2. Nodal marginal zone lymphoma

3. Burkitt lymphoma

4. Primary effusion lymphoma

5. ALK+ large B cell lymphoma

6. Large B cell lymphoma arising in HHV8 associated multicentric Castleman disease

7. Intravascular large B cell lymphoma

Part 2

1. ALK-positive large B-cell lymphoma.

2. Plasmablastic lymphoma.

3. B-cell prolymphocytic leukemia.

4. Splenic marginal zone lymphoma.

5. B lymphoblastic leukemia/lymphoma.

6. Hairy cell leukemia.

7. Splenic B-cell lymphoma/leukemia, unclassifiable.

Part 3

1. Monoclonal gammopathy of undetermined significance

2. Plasma cell myeloma

3. Extraosseous plasmacytoma

4. Solitary plasmacytoma of bone

5. Amyloidosis

6. Extranodal marginal zone lymphoma

7. Follicular lymphoma

8. Primary cutaneous follicular lymphoma

9. Mantle cell lymphoma

Part 4

1. Diffuse large B cell lymphoma

2. T cell/histiocyte-rich large B cell lymphoma

3. Primary CNS lymphoma

4. Primary mediastinal large B cell lymphoma

5. EBV+ diffuse large B cell lymphoma of the elderly

6. Primary cutaneous large B cell lymphoma, leg type

7. Diffuse large B cell lymphoma associated with chronic inflammation

8. Lymphomatoid granulomatosis

9. B cell lymphoma, unclassifiable, DLBCL/Burkitt

10. B cell lymphoma, unclassifiable, DLBCL/Hodgkin

11. Heavy chain diseases

Part 5

1. Variety of diffuse large b cell lymphoma subtypes

2. Lymphomatoid granulomatosis

3. Heavy chain diseases

4. Primary CNS lymphoma

5. Post-transplant lymphoproliferative disorders

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include B cell lymphoma, lymphoma, non-Hodgkin lymphoma, myeloma, amyloidosis, MGUS, heavy chain disease, lymphomatoid granulomatosis, primary CNS lymphoma, diffuse large B cell lymphoma, post-transplant lymphoproliferative disease, lymphomatoid granulomatosis, primary cutaneous diffuse large B cell lymphoma, t cell rich large B cell lymphoma, and primary mediastinal large B cell lymphoma.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)
☑  Practice-Based Learning (PBL)

Supported Computer Hardware and Software Configurations1

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.