10034 - The Cutaneous Histiocytoses

Course Director

May P. Chan, M.D., University of Michigan


Cutaneous histiocytoses are relatively rare disorders that most physicians have little experience with. This course is an up-to-date review of the clinical and pathologic features of these disorders with abundant high resolution images that illustrate key histopathologic features for diagnosis. The information and illustrations in this course can be used as a ready reference for practicing Pathologists, Dermatopathologists, Dermatologists, Pediatricians, and other physicians.


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

2.0 ABP CC/MOC Credits1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: $52.00

Course Dates

Last Review Date: 31-Aug-2023
Expiration Date: 30-Aug-2026


The need for physicians to:

1. To understand the classification of histiocytoses and related disorders

2. To learn the clinical and histologic features of different types of histiocytoses, with emphasis on clinicopathologic correlation

3. To become familiar with the immunophenotypes of different histiocytes and their pathologic correlates

4. To know the proper work-up of histiocytic cases for pathologists to render accurate diagnoses.


1. Definition and differentiation of histiocytes

2. Langerhans cell histiocytosis

3. Indeterminate cell histiocytosis

4. Xanthogranulomas

5. Rosai-Dorfman disease

6. Xanthomas associated with hyperlipidemia

7. Necrobiotic xanthogranuloma

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include histiocytes, Langerhans cell histiocytosis, indeterminate cell histiocytosis, xanthogranuloma, Rosai-Dorfman disease, plane xanthoma, tuberous xanthoma, papular xanthoma, hyperlipidemia, and necrobiotic xanthogranuloma.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)
☑  Practice-Based Learning (PBL)

Financial Relationship Disclosure and Content Attestation

Dr. May P. Chan, Course Director, attests that she has no financial relationships with a commercial entity producing health-care related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not produce health-care related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that produce health care-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 CC/MOC credits for the American Board of Pathology (ABP) Continuing Certification (CC) / Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn CC/MOC credits equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABP CC/MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.