10041 - Hemophagocytic Lymphohistiocytosis: From Pathogenesis to Treatment

Course Director

Yury Sheykin, M.D., Ph.D., Harvard Medical School

Description

Hemophagocytic lymphohistiocytosis (HLH)is a serious life threatening disorder that must be recognized early for effective medical intervention. Yet many clinicians and pathologists have limited experience recognizing the symptoms and signs of HLH. A review of the salient features and types of HLH is needed for physicians to improve recognition and intervention in this disorder, and outcome of patients presenting with HLH. This course reviews the historical recognition, clinical features, and key laboratory abnormalities to enable early identification and timely treatment of this often fatal disorder.

Credits

AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

0.75 ABP SAM for MOC Credits1
0.75 ABIM MOC Points2

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: $18.00

Course Dates

Last Review Date: 21-Dec-2016
Expiration Date: 21-Dec-2019

Objectives

To review historical recognition, clinical types, clinical features, laboratory abnormalities, and bone marrow biopsy findings in patients with hemophagocytic lymphohistiocytosis (HLH).

Topics

The course will cover genetic basis, pathophysiology, classification, clinical presentation, pathologic and laboratory diagnosis, and basics of treatment of HLH. Historical aspects will also be covered.

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include Hemophagocytic lymphohistiocytosis, HLH, Hemophagocytic syndrome, Macrophage activation syndrome, Hemophagocytosis, NK cell, NKT cell, cytotoxic T cell, and cytotoxic granules.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)
☑  Practice-Based Learning (PBL)

Financial Relationship Disclosure and Content Attestation

Dr. Yury Sheykin attests that he has no financial relationships with a commercial entity producing health-care related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not produce health-care related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that produce health care-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations3

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).


1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75 Self Assessment Module (SAM) Credits in the American Board of Pathology (ABP) Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn SAM for MOC credits equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Upon course completion, participants may download a completion certificate as evidence of completion.

2. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75 MOC points in the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn MOC points equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

3. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.