10048-001 - Myeloid Neoplasia: A Review of Clinical Features and Diagnostic Criteria. Part 1: The Myelodysplastic Syndromes

Course Director

David Hudnall, M.D., Yale University School of Medicine


This course is part 1 of a 3 part series that covers the diagnostic criteria and clinicopathologic features of the myelodysplastic syndromes (part 1), the myeloproliferative neoplasms (part 2), and the acute myeloid leukemias (part 3).


This course is part of a series (click on series name below for information.)

10048 - Myeloid Neoplasia: A Review of Clinical Features and Diagnostic Criteria


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

1.0 ABP CC/MOC Credits1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course: Free
Credits: $26.00

Course Dates

Last Review Date: 27-Aug-2020
Expiration Date: 27-Aug-2023


After completion of this course, registrants will be able:

1. To delineate the specific diagnostic criteria for all WHO-defined myelodysplastic syndromes, including clinical, histologic, immunophenotypic, and genetic features.

2. Differentiate the specific subtype of myelodysplastic syndrome in clinical cases using clinical, histologic, immunophenotypic, and genetic criteria.


1. Myelodyplastic syndromes (MDS) defined.

2. Cytogenetic defects in myelodysplastic syndromes.

3. Refractory cytopenia with unilineage dysplasia (RCUD).

4. Refractory anemia with ring sideroblasts (RARS).

5. Refractory cytopenia with multilineage dysplasia (RCMD).

6. Refractory anemia with excess blasts (RAEB).

7. Therapy-related MDS (tMDS).

8. MDS with isoltaed del(5q).

9. MDS, unclassifiable.

10. Childhood MDS.

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include MDS, myelodysplasia, myelodysplastic syndrome, refractory cytopenia with unilineage dysplasia (RCUD), refractory anemia with ring sideroblasts (RARS), refractory cytopenia with multilineage dysplasia (RCMD), refractory anemia with excess blasts (RAEB, therapy-related MDS (tMDS), MDS with isoltaed del(5q), and childhood MDS.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)
☑  Practice-Based Learning (PBL)

Financial Relationship Disclosure and Content Attestation

Dr. David Hudnall attests that he has no financial relationships with a commercial entity producing health-care related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not produce health-care related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that produce health care-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 CC/MOC credits for the American Board of Pathology (ABP) Continuing Certification (CC) / Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn CC/MOC credits equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABP CC/MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.