10114 - The Genetics of Asthma and Allergic Disease: A 21st Century Perspective

Course Directors

Carole Ober, Ph.D., University of Chicago
Tsung-Chieh Yao, Chang Gung University College of Medicine, Taoyuan, Taiwan


Asthma and allergy are common conditions with complex etiologies involving both genetic and environmental contributions. This course summarizes the genetic studies of asthma and allergic diseases that have been conducted over the past 40 years, with emphasis on studies completed in the past 5 years and, in particular, on results of genome-wide association studies. It discusses asthma and allergy susceptibility genes and the common and unique biological pathways that are dysregulated in these related conditions.


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

2.0 ABIM MOC Points1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: $52.00

Course Dates

Last Review Date: 03-Apr-2022
Expiration Date: 02-Apr-2025


After completing this course, participants will understand:

1) Epidemiology of asthma and allergy.

2) Clinical heterogeneity and intermediate phenotypes.

3) Environmental modifiers of asthma and allergy.

4) Asthma and allergy gene discoveries.

5) Relationship between asthma and allergic disease.


1) Asthma and Allergic Diseases

2) Environment Modifiers of Asthma and Allergy

3) Approaches for Discovering Asthma and Allergy Genes

4) An Overview of Asthma and Allergy Gene Discoveries

5) Meta-analyses of Genome-wide association studies (GWAS)

6) 'Missing Heritability' in Asthma and Allergic Diseases

7) Other Considerations

8) Asthma and Allergic Disease: Same Disease or Shared Pathways?

9) Concluding Remarks and Future Directions

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include Asthma, allergy, allergic, atopy, atopic dermatitis, and genome-wide studies.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)

Financial Relationship Disclosure and Content Attestation

Drs. Carole Ober and Tsung-Chieh Yao attest that they have no financial relationships with a commercial entity offering healthcare related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not offer healthcare related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that offer healthcare-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 MOC points for the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn MOC points equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.