10167 - A Contemporary Approach to Prostate and Renal Pathology

Course Director

Michelle Hirsch, M.D., Ph.D., Harvard Medical School


This course reviews the prostate cancer Gleason Grading System and modifications, and the 2014 International Society of Urological Pathology (ISUP) Consensus Conference new grading scheme. It reviews how to interpret volume in biopsy cores and prostatic intraductal carcinoma versus invasive cribriform carcinoma. This course also updates the WHO classification of renal cell carcinoma (RCC), including detailed descriptions of clear cell (tubulo)papillary RCC, acquired cystic disease-associated RCC, tubulocystic RCC, succinate dehydrogenase deficient RCC, hereditary leiomyomatosis RCC, and reviews familial syndromes with epithelial kidney tumors.


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

2.0 ABP CC/MOC Credits1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: $52.00

Course Dates

Last Review Date: 23-Nov-2020
Expiration Date: 23-Nov-2023


After completing this course physicians are expected to have improved understanding of:

1. Prostate cancer, the Gleason Grading System, and the new grading system from the 2014 Consensus Conference.

2. Kidney cancer and the 2004 and 2016 WHO Adult Renal Cell Carcinoma classification systems.


1. Gleason grading system and modifications

2. ISUP Gleason Grading Consensus Meeting in 2005

3. Active Surveillance and triggers to treat

4. 2012 Working Group and Consensus Statement on Gleason Grading System

5. 2014 Prostate and ISUP Consensus Conferences

6. Intraductal Carcinoma of the Prostate

7. Invasive cribriform prostatic carcinoma

8. 2014 ISUP Consensus Conference: New Grading Scheme

9. How to interpret tumor volume of cores

10. WHO classification of renal cell carcinomas (RCC): update

11. Clear cell (tubulo)papillary RCC

12. Acquired cystic disease-associated RCC

13. Tubulocystic RCC

14. Familial syndromes with epithelial kidney tumors

15. Succinate Dehydrogenase deficient RCC

16. Hereditary Leiomyomatosis RCC

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include prostate cancer, Gleason grading, ISUP new grading scheme, clear cell (tubulo)papillary renal cell carcinoma, acquired cystic disease-associated renal cell carcinoma, tubulocystic renal cell carcinoma familial syndromes with epithelial kidney tumors, succinate dehydrogenase deficient renal cell carcinoma, and hereditary leiomyomatosis renal cell carcinoma.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)

Financial Relationship Disclosure and Content Attestation

Dr. Michelle Hirsch attests that she has no financial relationships with a commercial entity offering healthcare related products and/or services. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not offer healthcare-related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that offer healthcare-related products or services relevant to the course content.

There has been no commercial support for this course.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 CC/MOC credits for the American Board of Pathology (ABP) Continuing Certification (CC) / Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn CC/MOC credits equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABP CC/MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.