10223 - New Strategy: Steroid-Resistant Focal Segmental Glomerulosclerosis

Course Director

Eri Muso, M.D., Ph.D., Kyoto Kacho University

Description

Primary focal segmental glomerulosclerosis (FSGS) has become one of the most common causes of idiopathic glomerular disease in adults. The incidence of primary FSGS has increased by 3- to 13-fold during the last 20-30 years. FSGS is a progressive form of renal disease and has become the most common cause of GN-related end-stage renal disease. This course presents an update on what is known and not known about FSGS, reviews results of steroid/immunosuppressive therapy, and results of more recent use of lipid apheresis.

Credits

AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

1.25 ABIM MOC Points1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: Free

Course Dates

Offered Date: 25-Aug-2020
Expiration Date: 25-Aug-2023

Objectives

After taking this course, learners are expected to be able to:

1. Describe clinical characteristics of primary focal segmental glomerulosclerosis (FSGS).

2. Identify pathogenesis of FSGS along with lipid nephrotoxicity.

3. Describe the beneficial effect of LDL apheresis in the treatment of refractory FSGS.

4. Describe hypothetical mechanism of action of LDL apheresis in FSGS.

Topics

1. Clinical features of FSGS.

2. Pathogenesis of FSGS along with lipid nephrotoxicity.

3. Effect of LDL apheresis as treatment of refractory FSGS.

4. Hypothesis for mechanism of action of LDL apheresis in FSGS.

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include focal segmental glomerulosclerosis, FSGS, and LDL apheresis.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)
☑  Medical Knowledge (MK)

Financial Relationship Disclosure and Content Attestation

Dr. Eri Muso, course director, discloses that she has previously been a lecturer for Kaneka. She attests that they have had no influence on the course content. Dr. Kirk Campbell, moderator, discloses that he has consulted for Retrophin and Vertex Pharmaceuticals and has been a research grant recipient from Mallinckrodt Pharmaceuticals and Goldfinch Bio. He attests that none of these entities have had an influence on the course content. Dr. Paul VanderLaan, reviewer, discloses that he has consulted in an advisory capacity for Gala Therapeutics, Caris Life Sciences, Foundation Medicine, Flatiron Health, Intuitive Surgical, and Clearview Healthcare Partners. He attests that none of these entities have had an influence on the course content or his review thereof. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not offer healthcare-related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that offer healthcare-related products or services relevant to the course content. Financial support for this course has been received from Kaneka Pharma America, LLC, which has had no influence on the course content.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).


1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 MOC points for the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn MOC points equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.