10232 - Focal Segmental Glomerulosclerosis: Pathophysiology and Approach to Therapy

Course Directors

Abdallah Geara, M.D., University of Pennsylvania
Jonathan Hogan, M.D., University of Pennsylvania
Joshua Zaritsky, M.D., Ph.D., St. Christopher's Hospital for Children


This course reviews the definition of primary and secondary focal segmental glomerulosclerosis (FSGS), the epidemiology of FSGS, and presents an approach to diagnosis and management of FSGS.


AMA PRA Category 1 Credits™

Opus Medicus designates this Internet enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification (MOC) Credits

In addition to AMA PRA Category 1 Credits™, Opus Medicus designates this course for Specialty Board MOC Program Credits:

1.0 ABIM MOC Points1

Accreditation Statement

Opus Medicus is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Tuition Fees

Course & Credits: Free

Course Dates

Offered Date: 18-Nov-2020
Expiration Date: 18-Nov-2023


After taking this course, learners are expected to be able to:

1. Define focal segmental glomerulosclerosis (FSGS)

2. Understand the epidemiology of FSGS

3. Generate an approach to diagnosis of FSGS

4. Understand the management of FSGS


1. Definition of primary and secondary FSGS

2. Epidemiology of FSGS

3. Pathogenesis of primary and secondary FSGS

4. Prognostic factors of FSGS

5. Approach to therapy of FSGS

6. Novel therapies of FSGS

Specific topics covered in this AMA PRA Categogy 1 Credit™ online CME course include focal segmental glomerulosclerosis, FSGS, and lipid apheresis.

American Board of Medical Specialties (ABMS) / Accreditation Council for Graduate Medical Education (ACGME) Competencies

☑  Patient Care (PC)

Financial Relationship Disclosure and Content Attestation

Dr. Joshua Zaritsky and Dr. Abdallah Geara, course directors, attest that they have no financial relationships with a commercial entity offering healthcare related products and/or services. Dr. Jonathan Hogan, moderator, discloses that he has consulted for Retrophin and Complexa, has received research grants from Retrophin, Complexa, and BMS, and is on an advisory committee for Zyversa. He attests that none of these entities have had an influence on the course content. Dr. Paul VanderLaan, reviewer, discloses that he has consulted in an advisory capacity for Gala Therapeutics, Caris Life Sciences, Foundation Medicine, Flatiron Health, Intuitive Surgical, and Clearview Healthcare Partners. He attests that none of these entities have had an influence on the course content or his review thereof. Dr. Steven R. Tahan, Education Committee Chair, attests that commercial entities with which he has relationships do not offer healthcare-related products or services relevant to the content of this course. No other person who has provided content for or who can influence the content of this course has disclosed financial relationships with commercial entities that offer healthcare-related products or services relevant to the course content. Financial support for this course has been received from Kaneka Pharma America, LLC, which has had no influence on the course content.

Supported Computer Hardware and Software Configurations2

Supported client computing platforms include:

A broadband Internet connection is required (e.g., cable, DSL, and 3G or 4G wireless). The course presentation is automatically scaled to the size of the display, from 800x480 pixels (minimum supported) to 1920x1200 pixels. On some smart phones, viewing courses may be tedious.

Supported browsers include:

Javascript, cookies, and popups must be enabled on your browser (which is the default configuration for most browsers).

1. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points for the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) Program, in addition to AMA PRA Category 1 Credits™. Participants will earn MOC points equivalent to the amount of AMA PRA Category 1 credits claimed for the activity. Immediately upon course completion, Opus Medicus will submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

2. The course may also be viewable on other client computing platforms that comply with Internet standards. If you experience technical problems that prevent you from viewing the course, we will promptly issue a full refund upon request.